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Four MCMC chains were run simultaneously from random trees for ten million generations, sampled every 1000 generations and repeated twice
This is further exacerbated by the relatively low predictive ability of current polygenic risk scores, which, even when using more ancestrally homogenous and large cohorts such as the FinnTwin12 study, the PRS explained between 2.5 to 3.5% of the variance for alcohol use disorder [64]
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